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. 2021 Oct 29;86(23):16824–16833. doi: 10.1021/acs.joc.1c02046

Table 1. Comparison of the Activity (GI50) of Compounds 40 and 41 to Representative Schweinfurthins against Selected CNS Cell Lines.

compound # (NSC number) SF-295 (μM) SF-539 (μM) SNB-75 (μM) Pearson correlation to 1
1 (696119) 0.011 0.010 0.015 1.00
44 (730430)a 1.5 – 15.8 0.39
14 (740545) 0.066 0.28 0.18 0.78
40 (819974) 3.0 1.3 1.8 0.66
41 (823234) 0.51 0.98 1.0 0.66