Table 1. Optimization Studies for Palladium-Catalyzed Synthesis of (p-Tolyl)diphenylphosphine Oxide (2a).

entry	additive (equiv)	time (h)	temperature (°C)	isolated yield (%)
1a		24	90	41
2		24	110	58
3		24	120	79
4	NaOAc (1)	22	120	55
5	NaCl (1)	32	120	64
6	NaI (1)	4	120	78
7	NaI (0.1)	8	120	76

^aUsing 1 equiv of Ph₂P(O)H.