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. 2021 Nov 16;25(24):11310–11321. doi: 10.1111/jcmm.17062

FIGURE 1.

FIGURE 1

CIRP expression increases in human DCD livers during cold storage. (A) A total of 41 UW specimens were collected after cold storage. CIRP expression in the CS>5 h group was 2.4 times higher than that in the CS≤5 h group. Data are shown as mean ± SEM, *p < 0.05. (B) The CS>5 h group had lower TFAM expression compared to the CS≤5 h group. Data represent mean ± SEM, *p < 0.05. (C) Serum specimens from 30 patients were analysed at five time points. Serum CIRP levels reached the peak at 2 h after reperfusion (R2h) and returned to preoperative levels 1 day after the operation (POD1). Data are shown as mean ± SEM, *p versus the anaesthesia group, # p versus the POD1 group. (D) The expression of CIRP and IL‐6 at R2h are positively correlated (r = 0.8685, p < 0.001). (E) The expression of CIRP at R2h was positively correlated with ALT at POD1 (r = 0.6590, p < 0.001). (F) The expression of CIRP at R2h was positively correlated with AST at POD1 (r = 0.7341, p < 0.001)