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. 2021 Nov 10;25(24):11212–11220. doi: 10.1111/jcmm.17042

TABLE 2.

Influence of NAFLD on the severe event in subgroups of COVID‐19 patients according to gender, age, BMI and comorbidities

Severe event (n, %) p value Virus shedding time (days) p value Length of hospital stay (days) p value

NAFLD

(n=86)

Non‐NAFLD

(n = 132)

NAFLD

(n=86)

Non‐NAFLD

(n = 130)

NAFLD

(n=86)

Non‐NAFLD

(n = 130)

Gender
Male 12 (23.1%) 13 (22.4%) 0.934 17 (6–47) 17.5 (6–42) 0.696 14 (5–41) 17 (5–37) 0.689
Female 7 (20.6%) 9 (12.2%) 0.252 17.5 (1–38) 19 (5–53) 0.131 17 (5–37) 16 (5–40) 0.569
Age
Elderly (≥ 60 years) 5 (25%) 13 (35.1%) 0.432 16 (4–38) 23 (11–43) 0.011 17 (6–37) 21 (6–40) 0.155
Non‐elderly (< 60years) 14 (21.2%) 9 (10.5%) 0.036 17.5 (3–47) 17 (6–53) 0.975 15 (5–41) 15 (5–40) 0.986
BMI
BMI ≥24 kg/m2 7 (14.6%) 7 (23.3%) 0.327 18.5 (8–47) 21 (6–45) 0.595 15 (5–41) 17 (6–40) 0.643
18.5 ≤ BMI <24 kg/m2 9 (30%) 9 (11.5%) 0.021 17 (3–38) 17 (8–53) 0.939 16.5 (5–37) 16 (5–37) 0.697
BMI <18.5 kg/m2 NA 3 (21.4%) NA NA 18.5 (8–40) NA NA 14.5 (8–40) NA
Hypertension
Yes 9 (45%) 4 (33.3%) 0.780 16.5 (11–45) 18 (12–43) 0.366 16.5 (5–41) 21 (8–35) 0.387
No 10 (15.2%) 18 (15.0%) 0.978 17.5 (3–47) 18.5 (6–53) 0.138 16.5 (11–45) 18 (12–43) 0.348
Cardiovascular disease
Yes 2 (66.7%) 2 (40.0%) 1.000 21 (19–29) 35 (22–29) 0.114 22 (19–27) 24.5 (14–35) 0.857
No 17 (20.5%) 20 (15.7%) 0.379 17 (3–47) 18 (6–53) 0.205 15 (5–41) 16 (5–40) 0.411
Diabetes
Yes 2 (22.2%) 2 (40.0%) 0.580 15 (9–29) 27 (15–43) 0.112 15 (6–30) 28 (17–32) 0.060
No 17 (22.1%) 20 (15.7) 0.255 17 (3–47) 18 (6–53) 0.259 15 (5–41) 16 (5–40) 0.560
Chronic liver disease
Yes 2 (40.0%) 1 (16.7%) 0.545 16 (14–29) 24 (11–34) 0.537 13 (9–27) 22 (8–36) 0.662
No 17 (21.0%) 21 (16.7%) 0.433 17 (3–47) 18 (6–53) 0.188 15 (5–41) 15 (5–40) 0.496

Abbreviations: NAFLD, Non‐alcohol fatty liver disease; BMI, Body mass index; NA, Not available.