FIGURE 3.

Dysfunctional gatekeeping of the global workspace leads to aberrant perceptions that invade conscious awareness. The anterior insula (AI) continuously monitors inputs from brain areas including the hypothalamus (HT), auditory cortex (AUD) and periaqueductal gray (PAG). Working with the dorsal anterior cingulate cortex (dACC), these cortical hubs of the salience network select the most relevant information (from unimportant background noise) for conscious broadcast to the global workspace. In the case of auditory hallucinations, dysfunctional gatekeeping of the global workspace by the core cortical hubs of the salience network may result in inadvertent broadcast of auditory representations (e.g., voices, sounds) to conscious awareness in some individuals with schizophrenia.