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. 2021 Nov 23;15:729482. doi: 10.3389/fnana.2021.729482

FIGURE 3.

FIGURE 3

Dynamic motor evoked potentials (DMEPs) illustrating. (A) Electrode placement. To elicit the motor evoked potentials (MEPs), anodal stimuli (Stim) and a reference (Ref) electrodes were applied to the skull (C3 and C4). The responses were recorded from electrodes on the extensor digitorum communis in the forelimb and tibialis anterior in the hindlimb. (B) Representative images showing the N1 DMEPs in a sham group rat. The upper, middle and lower waves were DMEPs performed upon neutral, extension and flexion positions, respectively. (C–F) Representative images showing the N1 DMEPs in different time points of the CSM rats. The N1 waves of representative CSM rats at 3 and 4 weeks post-surgery upon flexion were abolished. (G–J) Quantification of DMEP amplitudes in CSM and sham groups at each time point. The DMEPs did not change at all neck positions after 10 min of implanting the unexpanded compression material. The DMEP amplitudes in CSM group did not change upon neutral and extension until 4 weeks post injury compared with the sham group. Upon flexion, the DMEPs in the CSM group deteriorated significantly compared with the other two neck positions, also with the flexion DMEPs in the sham group. **, *** indicated statistical significance (p < 0.01, 0.001, respectively) in the difference between the Sham and CSM group using t-test. # indicated statistical significance (p < 0.05) in the difference between different neck positions using one-way ANOVA and post hoc test.