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. 2021 Nov 23;12:763853. doi: 10.3389/fphar.2021.763853

TABLE 3.

Anthropometric parameters (mean ± SD) according to the PPARγ2 Pro12Ala genotype by sex.

Pro12Pro Pro12Ala Ala12Ala P a P b
Males (n = 499) n = 414 n = 81 n = 4
Non-adjusted
Weight (kg) 26,8 ± 5.3 27.2 ± 5.6 28.3 ± 3.4 0.514 0.323
BMI (kg/m2) 16.9 ± 2.4 17.1 ± 2.5 16.7 ± 1.4 0.850 0.855
Adjusted by leptin
Weight (kg) 26.6 ± 0.3 27.7 ± 0.6 28.3 ± 2.5 0.218 0.543
BMI (kg/m2) 16.8 ± 0.1 17.3 ± 0.3 17.0 ± 1.0 0.215 0.867
Females (n = 501) n = 422 n = 75 n = 4
Non-adjusted
Weight (kg) 26.7 ± 5.4 26.0 ± 5.4 32.5 ± 5.4 0.041 0.036
BMI (kg/m2) 17.0 ± 2.6 16.7 ± 2.0 20.4 ± 2.5 0.049 0.018
Adjusted by leptin
Weight (kg) 26.8 ± 0.3 25.7 ± 0.6 28.4 ± 2.1 0.143 0.404
BMI (kg/m2) 17.1 ± 0.1 16.9 ± 0.3 18.4 ± 0.9 0.265 0.132
a

p-value for comparison between groups by Kruskal-Wallis test.

b

p-value for comparison in a recessive model by Mann-Whitney U test.