TABLE 5.

Changing trends and significance results of the effects of the drugs on the toxicological indexes, taking the high-dose groups of CEF and LPEF water extracts (WE) for example.

Evaluating index	Comparison between the high dose of WE and the other groups
	CEF vs. control	LPEF vs. CEF	WE vs. VO in CEF	High dose vs. low dose in CEF
ATPases	↓↓	↑↑	↓↓	↓↓
AST	↑↑	↓↓	↑↑	↑↑
ALT	↑	↓↓	↑↑	↑↑
SOD	↓↓	↑↑	↓↓	↓
MDA	↑↑	↓↓	↑↑	↑↑
TNF-α	↑↑	↓↓	↑↑	↑↑
IL-6	↑	↓↓	↑↑	↑
IL-1β	↑↑	↓↓	↑↑	↑↑
Bax	↑↑	↓↓	↑↑	↑↑
Bcl-2	↓↓	↑↑	↓↓	↓↓
Caspase 3	↑↑	↓↓	↑↑	↑↑

↑, significant increase; ↑↑, very significant increase.

↓, significant decrease; ↓↓, very significant decrease.