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. 2021 Nov 23;8:787228. doi: 10.3389/fmed.2021.787228

Table 3.

The top 20 most cited works of literature on ORA.

Title Journal First Author Publication year Total citations
Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis Rheumatology Choy E 2012 420
Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA) Annals of the Rheumatic Diseases Dougados M 2014 406
Bone mineral density and frequency of osteoporosis in female patients with rheumatoid arthritis-Results from 394 patients in the Oslo County Rheumatoid Arthritis Register Arthritis and Rheumatism Haugeberg G 2000 363
Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis Arthritis and Rheumatism van Staa TP 2006 359
Low-dose prednisone therapy for patients with early active rheumatoid arthritis: Clinical efficacy, disease-modifying properties, and side effects-A randomized, double-blind, placebo-controlled clinical trial Annals of Internal Medicine van Everdingen AA 2002 341
Involvement of receptor activator of NF kappa B ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis Bone Romas E 2002 318
Biology of the RANKL-RANK-OPG system in immunity, bone, and beyond Frontiers in Immunology Walsh MC 2014 314
RANK/RANKL: Regulators of Immune Responses and Bone Physiology Annals of the New York Academy of Sciences Leibbrandt A 2008 280
Relationship between rheumatoid arthritis and periodontitis Journal of Periodontology Mercado FB 2001 255
Low-dose prednisolone in addition to the initial disease-modifying antirheumatic drug in patients with early active rheumatoid arthritis reduces joint destruction and increases the remission rate - A two-year randomized trial Arthritis and Rheumatism Svensson B 2005 251
IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor a from T cells Proceedings of the National Academy of Sciences of the United States of America Toraldo G 2003 209
1,25-Dihydroxyvitamin D-3 Modulates Th17 Polarization and Interleukin-22 Expression by Memory T Cells From Patients With Early Rheumatoid Arthritis Arthritis and Rheumatism Colin EM 2010 204
Osteoblast physiology in normal and pathological conditions Cell and Tissue Research Neve A 2011 201
Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies Annals of the Rheumatic Diseases Kleyer A 2014 192
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss Annals of the Rheumatic Diseases Krishnamurthy A 2016 184
Classical and paradoxical effects of TNF-alpha on bone homeostasis Frontiers in Immunology Osta B 2014 183
Bone remodeling in rheumatic disease: a question of balance Immunological Reviews Walsh NC 2010 166
Evaluation of bone mineral density, bone metabolism, osteoprotegerin and receptor activator of the NF kappa B ligand serum levels during treatment with infliximab in patients with rheumatoid arthritis Annals of the Rheumatic Diseases Vis M 2006 164
Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor Rheumatology Dayer JM 2010 159
A multicenter cross sectional study on bone mineral density in rheumatoid arthritis Journal of Rheumatology Sinigaglia L 2000 155