Table 3.
Performance characteristics for real-time PCR duplexes.
| Performance characteristic | CT/hDNA duplex | non-LGV/LGV duplex |
|---|---|---|
|
| ||
| Analytic sensitivity | 93%/100% | 100%/88% |
| Diagnostic sensitivity | 93%/100% | 100%/88% |
| Analytic specificity | 100%/100% | 100%/100% |
| Diagnostic specificity | n/aa / n/aa | 100%/100% |
| Precision/Reproducibility | 100% | 100% |
| Qualitative accuracy | 93% | 99% |
| Limit of detection (LOD) | ≤100 copies/reaction | ≤100 copies/reaction |
| Positive predictive value (PPV) | 100% | 100% |
| Negative predictive value (NPV) | 84% | 99% |
a
n/a, not applicable.