Table 2.

Summary of key published clinical studies examining the beneficial effects of the KD in neurological diseases.

Disease	Trial type	KD duration	Outcome	References
Alzheimer's disease	Randomized comparison of KD to high carbohydrate diet	6 weeks	Improved verbal memory performance	(29)
	Single-arm	12 weeks	Improved cognitive scores	(30)
	Randomized crossover	12 weeks	Improved quality of life, no improved memory	(31)
Dravet syndrome	Prospective study	3-12 months	Reduced seizures and hyperactivity	(32)
Epilepsy	Randomized, prospective and controlled	3 months	Reduced seizure frequency	(11)
Pharmacoresistant epileptic encephalopathy	Prospective study	12 weeks	Improved cognitive function, reduced seizure frequency	(33)
MS	Single-arm	6 months	Significantly improved fatigue and depression scores	(34)
	Randomized three-armed parallel grouped, single center, controlled	6 months	Improved quality of life and overall health	(35)
Parkinson's disease	Randomized, controlled, parallel-group trial	8 weeks	Small increase in cognitive abilities but no change in motor function	(36)