Figure 3.

Correlations between relative expression of five microRNAs (miRNAs) and CD4⁺ T cell counts in people with human immunodeficiency virus (HIV) infection. Relative expression of all miRNAs was significantly negatively correlated with the (A) the number of CD4⁺ T cells and (B) the proportion of CD4⁺ T cells after antiretroviral therapy (ART) in immune non-responders (INRs, n = 50) and immune responders (IRs, n = 50) in the mixed test set (p < 0.05). The increase in the proportion of CD4⁺ T cells was calculated using the following formula: (CD4⁺ T cell count after ART – CD4⁺ T cell count at baseline)/CD4⁺ T cell count at baseline. The y-axis represents the relative expression levels of each miRNA.