Table 2.
Performance parameters of the TGFβ pathway assay for diagnosis of pediatric sepsis and prediction of survival.
| Sepsis |
Sepsis diagnosis TGFβ PAS above normal
n = 492 |
Sepsis survival TGFβ PAS in normal range
n = 255 |
Sepsis non-survival TGFβ PAS above normal
n = 255 |
|---|---|---|---|
| Sensitivity | 64% | 32% | 69 |
| Specificity | 98% | 69% | 32 |
| PPV | 99% | 83% | 18 |
| NPV | 39% | 18% | 83 |
| Fisher's exact test | p <2.2e−16 | p = 1 | p = 1 |