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. 2021 Nov 23;12:758004. doi: 10.3389/fimmu.2021.758004

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Copyright © 2021 Chen, Wang, Song, Xu, Ruze and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of high expression of S100A2 in PC cancer cells and its association with poor prognosis. (A) The results of clustering and S100A2 expression distribution in single cell dataset CRA001160. (B) The expression difference of S100A2 between normal and pancreatic cancer cell lines detected by qRT-PCR. The difference between each PC cell line and HPNE was analyzed. (C) Representative images of low and high expression of S100A2 in PUMCH cohort (n = 65). (D–E) Correlation between S100A expression and T stage and differentiation status in PUMCH cohort. *P < 0.05; **P < 0.01; ***P < 0.001.