Table 1.
Demographics
| AD dementia (n = 220) | MCI converter (n = 70) | MCI converter | MCI non-converter (n = 94) | SCD (n = 40) | ||
|---|---|---|---|---|---|---|
| To AD dementia (n = 49) | To other dementia (n = 21) | |||||
| Age (years), mean (SD) and range |
76.9 (8.5) 50–91 |
75.0 (6.7) 55–91 |
74.8 (6.1) 55–91 |
75.4 (8.0) 57–89 |
69.7 (9.8)a 50–89 |
69.30 (9.2)a 51–85 |
| Follow-up duration (years), mean (SD) and range |
2.8 (1.7) 0.5–7.7 |
4.0 (1.9)a 1.2–8.7 |
4.1 (1.9) 1.2–8.7 |
3.8 (2.0) 1.2–7.0 |
3.2 (1.9) 0.5–7.8 |
3.46 (2.0) 1.0–7.7 |
| Education (years), mean (SD) and range |
14.4 (3.0)b 4–20 |
15.7 (2.8)a 10–20 |
15.9 (2.7) 10–20 |
15.3 (3.1) 12–20 |
15.3 (2.6) 10–20 |
15.6 (2.6) 10–20 |
| Female sex, N (%) | 135 (61) | 35 (50) | 25 (51) | 10 (48) | 39 (42)c | 16 (40)c |
| Caucasian race, N (%) | 202 (92) | 67 (96) | 47 (96) | 20 (95) | 86 (92) | 37 (93) |
| SAGE baseline, mean (SD) and range (maximum score 22) |
11.0 (4.4) 2–22 |
16.5 (3.1)a 8–22 |
16.4 (3.1) 9–21 |
16.6 (3.2) 8–22 |
17.0 (3.3)a 7–22 |
19.6 (2.0)a 14–22 |
| MMSE baseline, mean (SD) and range (maximum score 30) |
22.1 (3.7) 9–30 |
26.0 (2.4)a 19–30 |
26.0 (2.3) 19–30 |
26.2 (2.8) 20–30 |
27.4 (1.9)a 21–30 |
28.5 (1.4)a 23–30 |
Abbreviations: AD Alzheimer’s disease, MCI Mild cognitive impairment, MMSE Mini-Mental State Examination, SAGE Self-Administered Gerocognitive Examination, SCD Subjective cognitive decline, SD Standard deviation
aMean significantly different from the AD mean, from Tukey HSD test in a comparison of AD, MCI converter, MCI non-converter, and SCD groups
bEight missing
cSignificantly different from the AD proportion from Pearson chi-square test with Bonferroni correction for three comparisons