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. 2021 Dec 6;13:192. doi: 10.1186/s13195-021-00930-4

Table 2.

Least squares estimates of the slope for SAGE and MMSE score changes

Subgroup Change per year (SE) P value for zero slope
SAGE (22 points maximum) MMSE (30 points maximum) SAGE MMSE
MCI to AD dementia –1.91 (0.14) –1.68 (0.14) < .0001 < .0001
MCI to other dementia –2.33 (0.31) –1.83 (0.26)a < .0001 < .0001
AD dementia –1.82 (0.11) –2.38 (0.14) < .0001 < .0001
AD dementia, SAGE ≥5 (n = 202) –1.9 (0.11) –2.4(0.14) < .0001 < .0001
AD dementia, SAGE 2–4 (n = 18) 0.04(0.34) –2.17(0.68) 0.9161 0.0054
MCI con-converters 0.01 (0.09) –0.09 (0.05) 0.8907 0.0893
SCD 0.08 (0.08) –0.01 (0.08) 0.3168 0.8848

Abbreviations: AD Alzheimer’s disease, MCI Mild cognitive impairment, MMSE Mini-Mental State Examination, SAGE Self-Administered Gerocognitive Examination, SCD Subjective cognitive decline, SE Standard error

aOne outlier removed