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. 2021 Dec 7;18:57. doi: 10.1186/s12987-021-00285-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Brain/plasma lithium concentration ratios (%). A Acute and B long-term experiments. Brain/plasma ratios (%) estimated from values of the same animal as those shown in Figs. 4 and 5. P0 is not included in B as in long-term treated pups the dam’s treatment started from the day of birth. Note each point is an individual animal, blue points are samples measured using ICP-MS and black points are samples measured using LA-ICP-MS. Ages in brackets refer to age of fetus/pups when dams were also sampled. Means ± SD when n > 2, **p < 0.01, ***p < 0.001