Table 1.
Ages and numbers of rats used
| Age | P0 | P2 | P4 | P7 | P12 | P16/17 |
|---|---|---|---|---|---|---|
| A. Untreated fetuses/pups | ||||||
| n | 4 (2) | 3 (2) | 4 (4) | 4 (2) | 3 (3) | 3 (2) |
|
CR (mm) ± SD Weight (g) ± SD |
5 ± 0.4 | 8 ± 2 | 9 ± 1 | 16 ± 2 | 29 ± 5 | 45 ± 2 |
| Age | E18 | P0 | P2 | P4 | P7 | P12 | P16/17 |
|---|---|---|---|---|---|---|---|
| B. Acute fetuses/pups | |||||||
| n | 22 (2) | 3 (1) | 8 (2) | 43 (7) | 9 (3) | 6 (2) | 8 (3) |
|
CR (mm) ± SD Weight (g) ± SD |
23 ± 1 | 5 ± 0.4 | 8 ± 2 | 9 ± 3 | 17 ± 3 | 25 ± 4 | 48 ± 4 |
| Age | E18 | P2 | P4 | P7 | P12 | P16/17 |
|---|---|---|---|---|---|---|
| C. Long-term fetuses/pups | ||||||
| n | 23 (2) | 2 (1) | 6 (2) | 8 (2) | 1 | 7(2) |
|
CR (mm) ± SD Weight (g) ± SD |
22 ± 2 | 6, 8 | 11 ± 2 | 20 ± 1 | 40 | 50 ± 2 |
| Treatment group | Untreated | Acute E18 | Long term E18 | Acute Breast-feeding | Long-term breast feeding |
|---|---|---|---|---|---|
| D. Dams | |||||
| n | 1 | 2 | 2 | 2 | 2 |
|
CR (mm) ± SD Weight (g) ± SD |
312 | 431, 316 | 350, 336 | 354, 336 | 352, 310 |