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. 2021 Dec 6;11(12):e053169. doi: 10.1136/bmjopen-2021-053169

Table 1.

Demographic profile

All patients, n=140 Retrospective cohort, n=75 Prospective cohort, n=65 P value
Age in years, mean (SD) 39.6 (12.8) 39.6 (12.4) 39.5 (13.1) 0.80
Male sex 94 (67.1%) 51 (68%) 43 (67%) 0.81
Diabetes 7 (5%) 3 (4%) 4 (6.3%) 0.55
Hypertension 25 (17.9%) 15 (20%) 10 (15.6%) 0.51
Current smokers 51 (34.4%) 27 (36%) 24 (37.5%) 0.88
PLHIV 32 (22.9%) 14 (21.5%) 18 (29%) 0.21
CD4 count in cells/µL, median (Q1;Q3) 423 442 (137;568) 409 (204;568) 0.96
c-ART 23 (71.8%) 10/14 (71.4%) 13/18 (72%) 0.98
History of intravenous drug use 10 (7.1%) 5 (6.7%) 5 (7.7%) 0.93
History of valvular heart disease 40 (28.6%) 24 (32%) 16 (25%) 0.37
Previous cardiac surgery 20 (14.3%) 10 (13.3%) 10 (15.6%) 0.70
Definite IE by the modified Duke/ ESC 2015 clinical criteria2 83 (59.3%) 35 (46.7%) 48 (73.8%) <0.01

c-ART, combination anti-retroviral therapy; IE, infective endocarditis; PLHIV, people living with HIV.