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. 2021 Dec 6;11(12):e053169. doi: 10.1136/bmjopen-2021-053169

Table 3.

Baseline characteristics of BCPIE versus BCNIE in the prospective cohort

BCPIE (n=37) BCNIE (n=28) P value
Age (mean) 39.75 38.2 0.64
Male sex 23 (63.9%) 20 (71.4%) 0.44
Diabetes 4 (11.1%) 0
Hypertension 5 (13.9%) 5 (17.9%) 0.68
Current smokers 7 (27%) 17 (60.7%) <0.01
PLHIV 9 (25.7%) 9 (33.3%) 0.49
CD4 count cells/µL (mean) 347 470 0.67
c-ART 6 (66.7%) 7 (77.8%) 0.65
History of intravenous drug use 5 (13.5%) 0
History of valvular heart disease 9 (25%) 7 (25%) 1
Previous cardiac surgery 7 (19.4%) 3 (10.7%) 0.35
Antibiotic therapy prior to blood culture sampling 7 (19.4%) 10 (35.7%) 0.15
Surgery performed 19 20 0.11
In-hospital mortality 5 (13.5%) 4 (14.2%) 0.95

BCNIE, blood culture negative infective endocarditis; BCPIE, blood culture positive infective endocarditis; c-ART, combination anti-retroviral therapy; PLHIV, people living with HIV.