TABLE 3.
Accuracy of the synthetic post-therapeutic OCT images in determining the CMT and SRF in the evaluation experiment.
| Baseline | 1-month prediction | 3-month prediction | |||||
|---|---|---|---|---|---|---|---|
| CMT (μm) | Real images | Synthetic images | Real images | MAE (61 eyes) | Synthetic images | Real images | MAE (31 eyes) |
| Hd-PDT | 333.29 ± 132.53 | 198.32 ± 64.12 | 189.06 ± 61.49 | 28.21 ± 12.34 | 194.54 ± 63.71 | 187.29 ± 61.02 | 19.36 ± 8.44 |
| SML | 375.41 ± 151.86 | 264.39 ± 79.58 | 254.86 ± 77.67 | 34.14 ± 14.56 | 254.41 ± 78.01 | 248.32 ± 77.77 | 28.65 ± 10.28 |
| CL | 334.23 ± 121.82 | 244.17 ± 95.47 | 234.69 ± 93.95 | 31.12 ± 13.52 | 230.24 ± 76.54 | 220.23 ± 76.21 | 21.44 ± 9.68 |
| Total | 357.83 ± 142.32 | 240.56 ± 83.28 | 228.24 ± 81.08 | 30.15 ± 13.28 | 231.45 ± 77.64 | 220.92 ± 75.76 | 22.46 ± 9.71 |
| SRF (μm) | Real images | Synthetic images | Real images | MAE | Synthetic images | Real images | MAE |
| Hd-PDT | 206.54 ± 119.56 | 77.84 ± 79.84 | 75.65 ± 78.15 | 19.21 ± 20.47 | 65.47 ± 79.87 | 63.26 ± 79.14 | 17.84 ± 20.17 |
| SML | 229.65 ± 135.11 | 86.77 ± 87.65 | 82.52 ± 82.44 | 24.26 ± 25.54 | 74.18 ± 89.74 | 71.25 ± 88.62 | 21.04 ± 23.83 |
| CL | 210.32 ± 117.48 | 80.19 ± 84.21 | 79.34 ± 80.89 | 22.16 ± 24.05 | 69.05 ± 86.92 | 67.94 ± 85.87 | 19.83 ± 22.86 |
| Total | 217.56 ± 130.36 | 81.57 ± 81.54 | 78.35 ± 80.42 | 22.44 ± 23.14 | 70.07 ± 87.19 | 68.04 ± 86.53 | 19.33 ± 22.08 |
CMT, central macular thickness; SRF, subretinal fluid; PDT, photodynamic therapy, half-dose PDT (hd-PDT) was applied in our clinical protocol; SML, subthreshold micropulse laser treatment; CL, conventional laser treatment; MAE, mean absolute error, values are presented as the means ± standard deviations.