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Immunotherapy-related adverse events were affected by the gut microbiome. (A) The Kaplan-Meier method with log-rank test estimates the mPFS for patients with severe or mild diarrhea. (B) Gut microbiome alpha diversity comparison between the severe and mild diarrhea groups (Wilcoxon test). (C) Relative abundance comparison of significantly different taxa between patients with severe diarrhea and mild diarrhea (Wilcoxon test). mPFS, median progression-free survival.
