Fig. 2.

Mortalin regulates the RECK/STAT3 signaling pathway to promote the migration of hepatocellular carcinoma cells. A Western blot analyses of the expressions of mortalin, RECK, Flag-mortalin, p-STAT3, Ac-STAT3, and GAPDH in HCC cells with different mortalin levels. B Western blot assays of RECK, Flag, E-cadherin, N-cadherin, vimentin, and β-actin were performed. C HepG2 cells were subjected to migration assays, and D migrated cells were counted with Stat Monitor in Photoshop (mean ± SD, n = 3). ^*P < 0.05, statistically significant difference vs. vector cells. ^#P < 0.05 and ^{^}P < 0.05, statistically significant difference vs. vector cells treated with Flag-mortalin