Table 2.
Distribution of cell subpopulations in TCM syndrome types of CRC
| Cell types | Cell subpopulations | DES/Numbers (%) | DS/Numbers (%) | ES/Numbers (%) | P* |
|---|---|---|---|---|---|
| CRC cell | CEACAM5 + | 55 (37.67) | 3 (1.14) | 7 (19.76) | |
| EPCAM + | 0 (0.00) | 32 (12.17) | 19 (7.51) | ||
| KRT18 + | 1 (0.68) | 40 (15.21) | 6 (2.37) | ||
| MUC1 + | 1 (0.68) | 32 (12.17) | 9 (3.56) | ||
| Total | 57 (39.04) | 107 (40.68) | 41 (16.21) | < 0.001 | |
| Immune cell | Myeloid monomacrophage | 7 (4.79) | 65 (24.71) | 24 (9.49) | |
| DC | 10 (6.85) | 32 (12.17) | 25 (9.88) | ||
| T cell | 5 (3.42) | 25 (9.51) | 11 (4.35) | ||
| B cell | 14 (9.59) | 5 (1.90) | 11 (4.35) | ||
| Macrophage | 0 (0.00) | 22 (8.37) | 21 (8.30) | ||
| Total | 36 (24.66) | 149 (56.65) | 92 (36.36) | < 0.001 | |
| Stem cell | Stem cell | 4 (2.74) | 5 (1.90) | 21 (8.30) | < 0.005 |
| Fibroblast | EMT Like | 11 (7.53) | 0 (0.00) | 7 (2.77) | |
| CAFs | 0 (0.00) | 1 (0.38) | 38 (15.02) | ||
| Total | 11 (7.53) | 1 (0.38) | 45 (17.79) | < 0.001 | |
| Enterocyte | Enterocyte | 19 (13.01) | 0 (0.00) | 4 (1.58) | < 0.001 |
| Goblet cell | Goblet cell | 19 (13.01) | 1 (0.38) | 50 (19.76) | < 0.001 |
| Total | 14 | 146 | 263 | 253 |
*Chi-square test