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. Author manuscript; available in PMC: 2022 Jul 30.
Published in final edited form as: Clin Sci (Lond). 2021 Jul 30;135(14):1773–1789. doi: 10.1042/CS20210549

Figure 6. ET-1 receptor blockade attenuates increase in pro-inflammatory cells in eWAT in HFD-fed mice.

Figure 6.

Percent of total stromal fraction cells of CD4+, CD8+, eosinophils, NK, B, and F480+ (A–F) (n=5 per group) obtained by flow cytometry from eWAT of mice after 10 weeks on diet and 2 weeks of treatment with atrasentan or bosentan. Gene expression of Tnfα (G), Il-12b (H), and Il-10 (I) from eWAT of mice after 10 weeks on diet and 2 weeks of treatment with atrasentan or bosentan were determined via ddPCR (n=5 per group). Data were analyzed by one-way ANOVA with Tukey’s post-hoc test for individual groups. Data are expressed as mean ± SEM. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.