Table 1.
Clinical characteristics and laboratory parameters of COVID-19 patients by mortality.
| Variable | Died (n=12, 9.6%) | Recovered (n=112, 90.3%) | P |
|---|---|---|---|
| Age (years) | 79 (13.2, 64-91) | 58 (22.5, 14-86) | <.0001 |
| Charlson comorbidity index | 6.5 (2.1) | 2.2 (2.1) | <.0001 |
| Computerized tomography score | 6.0 (1.4) | 6.5 (3.4) | .665 |
| Pneumonia severity index | 111.9 (28.5) | 55.2 (24.7) | <.0001 |
| C-reactive protein (mg/L) | 41.4 (89.6, 3.51–170) | 25.6 (61.6, 0.1–237) | .231 |
| White blood cell count | 7513.3 (2584) | 6937.5 (2804) | .243 |
| Lymphocytes (%) | 14.6 (6.1) | 24.6 (11.9) | .006 |
| Thrombocytes (per mm3) | 197 108 (89131) | 211 734 (71981) | .426 |
| Hemoglobin (g/dL) | 10.9 (2.0) | 13.5 (1.7) | .0001 |
| Fasting glucose (mg/dL) | 134.0 (55) | 112.0 (24.9) | .04 |
| Serum creatinine (mg/dL) | 2.0 (2.2) | 0.95 (0.5) | <.001 |
| Percent change in serum creatininea (%) | 37.6 (95.5) | −6.8 (31.2) | <.0001 |
| Systolic blood pressure (mmHg) | 124.6 (16.3) | 123.3 (13.2) | .677 |
| Diastolic blood pressure (mmHg) | 72.5 (7.5) | 76.4 (6.2) | .023 |
| Procalcitonin (ng/mL) | 0.15 (0.38, 0.12–1.9) | 0.285 (0.553, 0–5.6) | .196 |
| Hospital stay (days) | 16 (6.75, 10–26) | 6 (5, 1–85) | <.0001 |
| Stay in ICU (days) | 13.5 (5.75, 3–22) | 0 (0, 0–46) | <.0001 |
| D-dimer (ng/mL) | 893 (820, 105–8600) | 1144 (568, 200–2200) | .04 |
| Alanine aminotransferase (U/L) | 20.5 (9.5, 6–114) | 24 (16, 10–154) | .28 |
| SaO2 (%) | 89.0 (9.2) | 95.0 (4.2) | .009 |
| O2 support (days) | 15.5 (3.25, 8–25) | 4.5 (5, 0–80) | <.0001 |
| APACHE scoreb | 48.5 (18.5) | 12.2 (9.7) | <.0001 |
| Number of antibiotics administered | 2.5 (0.5) | 1.4 (0.8) | <.0001 |
Data are median (interquartile range, min-mx) or mean (standard deviation).
aPercentage difference between the last serum creatinine and baseline serum creatinine.
bAPACHE score on admission to intensive care unit (ICU).