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. 2021 Jun 22;20(9):1614–1626. doi: 10.1158/1535-7163.MCT-20-0502

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©2021 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 5. The relationship between drug concentration and radiopotentiation in relation to genetic subtypes. Approximate radiotherapy DEFs at approximately 75% survival (aDEF75) of each inhibitor concentration determined by clonogenic assay across cell lines. aDEF75 values are the median of two independent experiments performed in triplicate, with error bars representing upper and lower limits. — The relationship between drug concentration and radiopotentiation in relation to genetic subtypes. Approximate radiotherapy DEFs at approximately 75% survival (aDEF₇₅) of each inhibitor concentration determined by clonogenic assay across cell lines. aDEF₇₅ values are the median of two independent experiments performed in triplicate, with error bars representing upper and lower limits.