Table 2:
Laboratory levels upon provocation tests.
| Basal | Stimulated | Mean difference (95% CI) | Percent change | p-value | ||
|---|---|---|---|---|---|---|
| Hypertonic saline infusion | ||||||
| Plasma copeptin (pmol/l) | 4.8 (2.4) | 33.5 (14.8) | 28.7 (21.7, 35.6) | 819.2 (762.4) | <0.001 | |
| Plasma oxytocin (pg/ml) | 0.4 (0.2) | 0.6 (0.3) | 0.2 (0.08–0.34) | 89.7 (136.6) | 0.003 | |
| Arginine infusion | ||||||
| Plasma copeptin (pmol/l) | 5.4 (3.8) | 9.4 (4.9) | 4.0 (3.1, 4.8) | 79.1 (54.3) | <0.001 | |
| Plasma oxytocin (pg/ml) | 0.5 (0.3) | 0.4 (0.2) | −0.04 (−0.15, 0.06) | 2.1 (55.6) | 0.4 | |
| Oral macimorelin test | ||||||
| Plasma growth hormone (ng/ml) | 12.5 (16.6) | 97.1 (40.0) | 85.3 (67.9, 102.7) | 13514.0 (19061.8) | <0.001 | |
| Plasma copeptin (pmol/l) | 5.0 (2.3) | 4.6 (2.3) | −0.38 (−0.6, −0.2) | −7.8 (11.1) | 0.002 | |
| Plasma oxytocin (pg/ml) | 49.7 (23.3) | 40.2 (16.1) | −10.6 (−21.4, 0.2) | −9.5 (36.7) | 0.05 | |
Basal and stimulated laboratory levels upon the hypertonic saline infusion, the arginine infusion and the oral macimorelin test with mean difference and percent change between basal and stimulated levels.
Continuous variables are presented as mean (standard deviation). Percent change represents the percent increase or decrease from basal and stimulated levels. Two group comparison was computed using the paired t-test.