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Inhibition of HSV-1 processive DNA synthesis by stapled peptides in a mechanistic in vitro DNA processivity assay. HSV-1 UL30 DNA Polymerase and UL42 Processivity Factor were translated in vitro and then used to conduct processive DNA synthesis in the presence of increasing amounts of Native (N) or Stapled (S) peptides. DNA synthesis was quantified via product-dependent colorimetry. The data represents mean ±SD from at least two independent experiments in triplicate
