TABLE 1.

Summary of cases, contacts with healthy individuals, and unrelated cases

Patient, healthy contact, or unrelated patient	Age (yr)	Gendera	Date of presentation (day/mo/yr)	Time (days) between discotheque visit and disease	Relationship to patient(s)	Clinical presentation	Site(s) yielding positive culture(s)	Serogroup	Serotype:serosubtype	PFGE pattern	porA gene subtypeb
											VR1	VR2	VR3
Patients
A	9	M	30/04/1992			Sore throat, septis	Blood	C	2a:nst	I	5a	10d	36b
B	2	F	11/05/1992			Septis	Blood	C	2a:nst	I	5a	10d	36b
C	24	M	28/06/1992	≈5		Septis, meningitis	Blood	C	2a:nst	I	5a	10d	36b
D	25	M	23/07/1992	5		Septisc	Blood, CSF	C	2a:nst	I	5a	10d	36b
E	21	F	24/07/1992	6		Arthritis	Knee joint	C	2a:nst	I	5a	10d	36b
F	21	M	25/07/1992	7		Conjunctivitis, meningitis	Blood, CSF, pharynx, socket	C	2a:nst	I	5a	10d	36b
G	21	M	09/09/1992	≈65		Arthritis, fever	Knee joint, pharynx	C	2a:nst	I	5a	10d	36b
Healthy contacts
1	25	M	26/07/1992		Boyfriend of patient E		Pharynx	C	2a:nst	I	5a	10d	36b
2	16	M	26/07/1992		Brother of patient D		Pharynx	C	15:P1.6	II	18	25b	38a
3	24	M	26/07/1992		Friend of patient D		Pharynx	C	4:nst	III	5a	10a	36b
4–10	1–52		26–28/07/1992		Contact with patients D, E, and F		—d
Unrelated patients
1	1	F	30/07/1992				CSF	C	2b:nst	IV	5	2b	36b
2	17	F	18/12/1992				CSF	C	15:P1.15	V	19	15a	36
3	24	M	30/12/1992				Blood	C	nt:P1.7,9	VI	7	9	35a
4	37	F	30/12/1992				CSF	C	2a:nst	VII	5	2	36b

^aAbbreviations: F, female; M, male. 

^bThe amino acid sequences of VR1 to VR3 (with subtypes in parentheses) were as follows: VR1, PLQNIQPQVTKR (5), PLQNIQQPQVTKR (5a), AQAANGGASGQVKVTKVTKA (7), PPSKGQTGNKVTKG (18), and PPSKSQPQVKVTKA (19); VR2, HFVQQTPKSQPTLVP (2), HFVQQPPKSQPTLVP (2b), YVDEQSKYHA (9), HFVQNKQNQPPTLVP (10a), HFVQNKQNKQNQPPTLVP (10d), HYTRQNNTDVFVP (15a), and TYTEGSSGVFTPVP (25b); and VR3, LLGSGSDQ (35a), LLGSTSDE (36), LLGSGSDE (36b), and LLGRIGEDDE (38a). 

^cFatal case. 

^dNo positive pharyngeal specimens.