FIGURE 6.

Tonic GABA current reduces excitability in VTA dopamine neurons. (a) Example traces of firing activity in response to current injections of increasing amplitude (starting holding potential of −60 mV) before and during the blockade of the tonic GABAergic current with PTX. (b) Graph of mean (+SEM) firing activity showing an increase in excitability following blockade of the tonic current (Group: p = 0.0116, Step: p = <0.0001, Interaction: p = 0.011). (c) Graph of mean (+SEM) input resistance (Rm) showing an increase after the blockade of the tonic GABAergic current with PTX (Before‐after interaction: p = 0.0093). *p < 0.05, **p < 0.01