Table 5.
Correlation between mean retinal vessel density and glaucoma duration, therapy duration, number of molecules used, global RNFL thickness, total GCC thickness, MD, and IOP values in XFG and POAG patients
| XFG group (n=50) | POAG group (n=48) | |||||||
|---|---|---|---|---|---|---|---|---|
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| Mean superficial pfVD (%) | Mean RPC pfVD (%) | Mean superficial pfVD (%) | Mean RPC pfVD (%) | |||||
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| R | P | R | P | R | P | R | P | |
| Glaucoma duration (years) | -0.123 | 0.394 | -0.081 | 0.577 | -0.785 | <0.001 | -0.750 | <0.001 |
| Therapy duration (years) | -0.139 | 0.334 | -0.069 | 0.632 | -0.792 | <0.001 | -0.742 | <0.001 |
| Number of molecules (n) | -0.003 | 0.985 | -0.269 | 0.059 | 0.165 | 0.264 | -0.188 | 0.201 |
| Mean IOP (mmHg) | 0.038 | 0.853 | -0.149 | 0.466 | 0.227 | 0.285 | -0.064 | 0.767 |
| Global RNFL (µm) | 0.332 | 0.105 | 0.530 | 0.006 | 0.412 | 0.046 | 0.720 | -0.001 |
| Total GCC (µm) | 0.212 | 0.299 | 0.450 | 0.021 | 0.185 | 0.386 | 0.526 | 0.008 |
| MD (dB) | -0.175 | 0.460 | -0.174 | 0.464 | 0.506 | 0.027 | 0.815 | -0.001 |
Pearson’s R (p value); Bold values are significant (p<0.05); GCC: Ganglion cell complex; IOP: Intraocular pressure; MD: Mean deviation; pfVD: Parafoveal vessel density; POAG: Primary open-angle glaucoma; ppVD: Peripapillary vessel density; RNFL: Retinal nerve fiber layer; RPC: Radial peripapillary capillary; XFG: Exfoliative glaucoma.