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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 May 27;41(7):2201–2214. doi: 10.1161/ATVBAHA.120.315788

Table 2.

Characteristics of subjects with plaque rupture compared to subjects who died from other causes

Variables Rupture n=124 Control (Death from other causes) n=640 p-value (unadjusted) p-value (adjusted) Odds Ratio Plaque Rupture 95% C.I.

Lower Upper
Age (mean ± SD) 52.02 ± 11.61 46.23 ± 12.75 <0.0001 <0.0001 1.035 1.019 1.052
Male Sex 99 (79.8%) 425 (66.4%) 0.003 0.005 2.025 1.240 3.306
BMI, kg/m2 (mean ± SD) 30.33 ± 7.06 29.97 ± 8.59 0.662 0.239 1.015 0.990 1.040
Hypertension 88 (71.0%) 400 (62.5%) 0.072 0.532 1.158 0.731 1.833
Smoking 11 (8.9%) 54 (8.4%) 0.874 0.744 1.126 0.552 2.296
Diabetes Mellitus 26 (21.0%) 91 (14.2%) 0.056 0.116 1.545 0.898 2.658
Hyperlipidemia 36 (29.0%) 84 (13.1%) <0.0001 <0.0001 2.308 1.443 3.690
CKD 9 (7.3%) 51 (8.0%) 0.788 0.174 0.579 0.263 1.274
APOL1 Risk Allele Carrier 85 (68.5%) 367 (57.3%) 0.020 0.021 1.655 1.079 2.539