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. 2021 Dec 7;16(12):e0260260. doi: 10.1371/journal.pone.0260260

Table 2. Sociodemographic and clinical profile stratified by Cognitive Reserve Index (CRI) with p-values from univariate analysis.

Variable Category CRI category Total p-value
Low-mediuma (n = 111) Mediumb (n = 100)
n, (%) n, (%)
Age M = 29 M = 31
18–29 years 60 (54.5) 50 (45.4) 110 0.74
30–39 years 39 (52.0) 36 (48.0) 75
≥ 40 years 12 (46.2) 14 (53.8) 26
Gender Females 83 (55.7) 66 (44.3) 149 0.16
Males 28 (45.2) 34 (54.8) 62
Marital status Single / Widowed 90 (52.0) 83 (48.0) 173 0.72
Married / Co-habiting 21 (55.3) 17 (44.7) 38
Educational attainment ≤ Grade 7 23 (100) 0 (0) 23 <0.01
Grade 8–11 61 (64.2) 34 (35.8) 95
≥ Grade 12 27 (29.0) 66 (71.0) 93
Employment status Employed—formal sector 24 (60.0) 16 (40.0) 40 0.52
Employed—Informal sector 31 (48.4) 33 (51.6) 64
Unemployed 56 (52.3) 51 (47.7) 107
Substance Use (any) No Substance Use 52 (54.7) 43 (45.3) 95 0.58
Substance Use (any) 59 (50.9) 57 (49.1) 116
Comorbid chronic illness No 98 (53.0) 87 (47.0) 185 0.78
Yes 13 (50) 13 (50) 26
Depression status Not depressed 99 (53.2) 87 (46.8) 186 0.62
Major depressive disorder 12 (48.0) 13 (52.0) 25
Suspected duration of HIV infection Infection not suspected at time of testing 70 (54.7) 58 (45.3) 128 0.63
Suspected infection in last 12 months 28 (51.9) 26 (48.1) 54
Suspected infection for > 12 months 13 (44.8) 16 (55.2) 29
CD4 count (n = 205) M = 401 M = 422
< 200 27 (58.7) 19 (41.3) 46 0.52
200–499 50 (53.2) 44 (46.8) 94
≥ 500 31 (47.7) 34 (52.3) 65

CRI, Cognitive Reserve Index.

a Cognitive Reserve Index Questionnaire (CRIq) score: 70–84;

b CRIq score: 85–114.