Figure 4.

The risk of incident ischaemic stroke according to alcohol consumption status. (A) The risk of incident ischaemic stroke in abstainers and current drinkers compared to non-drinkers. *With current drinkers as the reference group. Incidence rate, per 1000 person-years. (B) Stratifying current drinkers according to the amount of alcohol consumed per week. (C) Stratifying current drinkers according to the number of drinking sessions per week. (D) Stratifying current drinkers according to the alcohol consumed per each drinking session adjusted for age, sex, baseline body mass index, heavy drinker, regular exercise, low income, comorbidities including hypertension, diabetes mellitus, dyslipidaemia, heart failure, prior myocardial infarction, peripheral artery disease, chronic kidney disease, chronic obstructive pulmonary disease, cancer, CHA₂DS₂-VASc score, baseline medications including oral anticoagulants (warfarin or DOAC), anti-platelet agents (aspirin or P₂Y₁₂ inhibitor) and statin. CI, confidence interval; DOAC, direct oral anticoagulant; HR, hazard ratio; IR, incidence rate.