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. 2021 Nov 11;59(6):104. doi: 10.3892/ijo.2021.5284

Figure 1.

Figure 1

Identification of DEGs in thyroid cancer. The gene expression profiles of thyroid cancer tissues and normal tissues from (A) GSE and (B) TCGA datasets are presented as a volcano plot. The red dots represent the upregulated DEGs, while the blue dots represented the downregulated DEGs. (C) Overlapping results of the up- and downregulated DEGs from the two datasets. (D) The mRNA expression levels of ANXA1 in thyroid cancer tissues (n=512) and normal tissues (n=59) in TCGA dataset. *P<0.05. (E) Enrichment of ANXA1-regulated genes in apoptosis and cell-cell communication pathways. DEGs, differentially expressed genes, TCGA, The Cancer Genome Atlas; GSE, gene set enrichment; ANXA1, annexin A1.