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. 2021 Nov 11;59(6):104. doi: 10.3892/ijo.2021.5284

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Exosomal ANXA1 promotes malignant transformation of the Nthy-ori3-1 cells. The SW579 cells were transfected with ANXA1 shRNA2, ANXA1 OE or NC plasmids, then the Nthy-ori3-1 cells were co-cultured with exosomes isolated from the conditioned medium from the transfected SW579 cells. (A) Cell Counting Kit-8 assay, (B) flow cytometry assay and (C) Transwell assay was analyzed to determine proliferation, apoptosis and invasion, respectively. ^*P<0.05, ^**P<0.01. sh, short hairpin; OE, overexpression; NC, negative control; ANXA1, annexin A1; Exo, exosomes.