(c) Time to first SBM (mean difference and corresponding 95% Crls)
| Elobixibat 10 mg | ||||
| -8.362 (-22.320, 5.561) | Linaclotide 0.5 mg | |||
| -0.735 (-25.167, 22.572) | 7.620 (-17.334, 31.086) | Lubiprostone 48 μg | ||
| -8.072 (-24.794, 9.007) | 0.514 (-16.070, 16.286) | -7.219 (-32.774, 18.158) | Lactulose 26 g | |
| -26.438 (-36.588, -15.795) | -17.961 (-27.797, -8.897) | -25.481 (-47.119, -3.493) | -18.403 (-31.464, -5.301) | Placebo |