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| Investigação | Número de pacientes | |||
|---|---|---|---|---|
| 6 semanas | 12 semanas | 18 semanas | 24 semanas | |
| Radiografia (formação de calo ósseo) | 0 | 4 | 22 | 30 |
| Fosfatase alcalina (< 111 UI/L) | 0 | 0 | 8 | 30 |
| Ultrassonografia (sinal hiperecoico + diminuição do índice de resistência vascular) | 0 | 0 | 20 | 30 |
