Table 3.
Clinical Characteristics of 91 Patients With De Novo Calcified Nodules
| Overall | Restenosis | |||
|---|---|---|---|---|
| No | Yes | P value | ||
| No. patients | 91 | 62 | 29 | |
| Age (years) | 74.1±9.7 | 75.5±9.6 | 71.1±9.5 | 0.044 |
| Male sex | 63 (69.2) | 39 (62.9) | 24 (82.8) | 0.087 |
| Hypertension | 78 (85.7) | 53 (85.5) | 25 (86.2) | 1 |
| Diabetes | 42 (46.2) | 23 (37.1) | 19 (65.5) | 0.014 |
| Dyslipidemia | 64 (70.3) | 47 (75.8) | 17 (58.6) | 0.139 |
| Hemodialysis | 23 (25.3) | 12 (19.4) | 11 (37.9) | 0.072 |
| Prior PCI | 38 (41.8) | 22 (35.5) | 16 (55.2) | 0.11 |
| Prior CABG | 4 (4.4) | 4 (6.5) | 0 (0.0) | 0.302 |
| Lesion location (RCA/LMT-LAD/LCX) | 53/34/4 | 31/28/3 | 22/6/1 | 0.048 |
| Multivessel disease | 72 (79.1) | 49 (79.0) | 23 (79.3) | 1 |
| ACS | 49 (53.8) | 33 (53.2) | 16 (55.2) | 1 |
| Lesion characteristics | ||||
| ≥99% stenosis | 38 (41.8) | 21 (33.9) | 17 (58.6) | 0.039 |
| Tortuous | 53 (58.2) | 31 (50.0) | 22 (75.9) | 0.024 |
| Mild/moderate/severe calcification (n) | 8/23/60 | 7/18/37 | 1/5/23 | 0.217 |
| Treatment strategy | ||||
| Rotational atherectomy | 52 (57.1) | 41 (66.1) | 11 (37.9) | 0.014 |
| Scoring balloon | 37 (40.7) | 25 (40.3) | 12 (41.4) | 1 |
| Drug-eluting stent | 73 (80.2) | 47 (75.8) | 26 (89.7) | 0.162 |
| Drug-coated balloon | 12 (13.2) | 10 (16.1) | 2 (6.9) | 0.325 |
| ELCA | 2 (2.2) | 1 (1.6) | 1 (3.4) | 0.538 |
Unless indicated otherwise, data are given as the mean±SD or n (%). ACS, acute coronary syndrome; CABG, coronary artery bypass grafting; ELCA, excimer laser coronary angioplasty; LAD, left anterior descending artery; LCX, left circumflex artery; LMT, left main trunk; PCI, percutaneous coronary intervention; RCA, right coronary artery.