Table 2.

Main characteristics of four studies included in the current meta-analysis.

ID	First Author, year	Country	Study design	Study population	Age distribution (years old)	Sex ratio (M/F)	No. of TMZ cycles (n)
							≤6	>6
1	Balana, 2020	Spain	RCT	159	≥ 18	83/76	79	80
2	Bhandari, 2017	India	RCT	40	18-65	24/16	20	20
3	Blumenthal, 2017	International	RCT	624	N/A	354/270	333	291
4	Refae, 2015	Egypt	RCT	59	19 – 72	47/12	29	30
Total				882	≥ 18	508/374	461	421

RCT, randomized clinical trial; TMZ, temozolomide; NA, not available.