Table 3.
Distribution of TNF-α gene genotype among cachectic NSCL cancer patients considering the cachexia severity.
| Variable | TNF-α 308G/A (rs1800629) | TNF-α 1031T/C (rs1799964) | ||
|---|---|---|---|---|
| Wild | Mutant | Wild | Mutant | |
| Cachexia severity | ||||
| Pre-cachexia (n = 10) | 9 (75) | 3 (25) | 7 (70) | 3 (30) |
| Cachexia (n = 23) | 8 (67) | 4 (33) | 20 (87) | 3 (13) |
| Refractory (n = 7) | 12 (75) | 4 (25) | 4 (57) | 3 (43) |
| χ2 | 2.0 p = 0.38 |
3.2 p = 0.2 |
||
Data are given as n (%). Statistical analysis was carried out using the chi-square test; p ≤ 0.05.
n (%), number (percentage); rs, referred sequence; TNF-α, tumor necrosis alpha subunit gene; χ2, chi-square value; NSCL, non-small cell lung.