Table 2.
Assessment of all Tumor Progression cases comparing false positives (central diffusion restriction) and true negatives (no central diffusion restriction)
| Tumor progression cases n = 36 |
Central restriction n = 13 (false positive cases) |
No central restriction n = 23 (true negative cases) |
p value |
|---|---|---|---|
| Histopathologic tumor Fraction (%) | 38 ± 21 | 46 ± 23 | > 0.05 |
| Patient age (years) | 62 ± 9 | 60 ± 11 | > 0.05 |
| Time from SRS to MRI (days) | 392 ± 221 | 415 ± 236 | > 0.05 |
| SRS dose (Gy) | 17.8 ± 5.0 | 17.8 ± 2.7 | > 0.05 |
| Additional WBRT (n) | 5/13 (38%) | 12/23 (52%) | > 0.05 |
| Primary tumor (n) |
Lung (7) Breast (4) Melanoma (1) Head and neck (1) |
Lung (13) Breast (4) Colorectum (2) Esophagus (2) Melanoma (1) Endometrium (1) |
WBRT whole brain radiotherapy
No significant differences were found between the two groups