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. 2021 Nov 24;12:772635. doi: 10.3389/fphar.2021.772635

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Copyright © 2021 Yang, Bi, Jin, Wang, Li, Li, He, Cui, Miao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Geniposide treatment regulated BAX, Bcl-2, Caspase 3, and Caspase 9 in liver fibrosis model mice. (A,B) Changes of the protein expression of BAX, Bcl-2, Caspase 3, Caspase 9, and β-actin in liver tissue. Geniposide treatment reversed the relative expression of the BAX, Bcl-2, Caspase 3, and Caspase 9 in model mice liver tissue. Control, model, and geniposide groups (n = 3 per group). #p < 0.05, Model group vs. Control group; ##p < 0.01, Model group vs. Control group; ∗p < 0.05 and ∗∗p < 0.01, Geniposide group vs. Model group.