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. 2021 Oct 20;125(12):1621–1631. doi: 10.1038/s41416-021-01587-4

Fig. 4. Refined CIN classification and association with response to neoadjuvant CTx and patients survival in the tumour biopsy cohort before CTx.

Fig. 4

The response to neoadjuvant CTx (a, c) and association with survival (b, d) is shown for patients with tumour biopsies before CTx in relation to the respective CIN-subgroup. CIN chromosomal instability, TRG tumour regression grade, 1Chi-squared test (overall). 2Cox’s regression.