Table 3.
Comparison of laboratory findings between SLE patients with and without thrombotic events.
| All (N = 259) | Thrombotic events (n = 27) | No event (n = 232) | P-value | |
|---|---|---|---|---|
| Laboratory findings | ||||
| White blood cells, 1,000/mm3 | 4.88 ± 2.66 | 5.37 ± 2.43 | 4.82 ± 2.68 | 0.148 |
| Lymphocytes, mm3 | 1.16 ± 0.66 | 1.26 ± 0.62 | 1.15 ± 0.64 | 0.373 |
| Hemoglobin, g/dL | 11.3 ± 6.67 | 11.1 ± 2.59 | 11.4 ± 6.98 | 0.459 |
| Platelet, × 103/μL | 183.1 ± 96.7 | 179.7 ± 108.2 | 183.5 ± 95.5 | 0.885 |
| ESR, mm/h | 48.5 ± 34.1 | 40.0 ± 29.9 | 49.7 ± 34.5 | 0.200 |
| CRP, mg/dL | 1.89 ± 2.45 | 0.09 ± 1.47 | 1.22 ± 2.54 | 0.241 |
| Serum creatinine, mg/dL | 0.78 ± 0.85 | 1.00 ± 1.05 | 0.75 ± 0.82 | 0.074 |
| Total cholesterol, mg/dL | 170.7 ± 54.9 (n = 249) | 194.2 ± 64.4 (n = 27) | 167.9 ± 53.2 (n = 222) | 0.046 |
| LDL-cholesterol, mg/dL | 97.7 ± 36.7 (n = 187) | 105.3 ± 36.8 (n = 20) | 96.7 ± 36.7 (n = 167) | 0.335 |
| Autoantibodies (%) | ||||
| Anti-nuclear | 227 (91.2) | 23 (88.5) | 204 (91.5) | 0.608 |
| Anti-Sm | 78 (30.2) | 7 (25.9) | 71 (30.7) | 0.607 |
| Anti-dsDNA | 147 (56.8) | 13 (48.1) | 134 (57.8) | 0.340 |
| Anti-RNP | 109 (42.2) | 9 (33.3) | 100 (43.3) | 0.322 |
| Anti-Ro/SS-A | 160 (61.8) | 18 (66.7) | 142 (61.2) | 0.581 |
| Anti-La/SS-B | 73 (28.2) | 9 (33.3) | 64 (27.6) | 0.530 |
| aPL | 54 (21.1) | 10 (37.0) | 44 (19.2) | 0.032 |
| Complement level (%) | ||||
| Decreased C3 level | 178 (68.1) | 16 (59.3) | 162 (69.8) | 0.262 |
| Decreased C4 level | 124 (47.9) | 11 (40.7) | 113 (48.7) | 0.282 |
Except where otherwise indicated, data are presented as the mean ± standard deviation.
aPL, anti-phospholipid antibody; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; SLE, systemic lupus erythematosus.