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. 2021 Dec 7;11:23550. doi: 10.1038/s41598-021-02813-y

Table 5.

Characteristics of patients with Parkinson’s disease (PD).

Characteristics Median (min–max)
Age (years) 66 (59–69)
Sex 9 men, 1 woman
Disease duration (years) 18 (10–22)
Medication as l-dopa equivalent dose (mg/day) a 416 (294–989)
DBS treatment duration (months) 37 (15–70)
DBS pulse settings
Right
 Amplitude (V) 3.3 (2.5–4.3)
 Pulse width (µs) 60 (60–90)
 Frequency (Hz) 145 (100–185)
Left
 Amplitude (V) 3.4 (2.2–4.3)
 Pulse width (µs) 60 (60–90)
 Frequency (Hz) 130 (100–185)
Positions of negative polarity contacts with reference to the intercommissural line midpoint
Right (mm)
 Lateral 11.7 (10.4–13.1)
 Posterior 3.4 (3.0–4.0)
 Inferior 2.1 (1.0–5.6)
Left (mm)
 Lateral 11.4 (9.6–13.0)
 Posterior 3.5 (3.3–5.2)
 Inferior 2.6 (1.2–4.2)
Intercommissural line (mm) 24.8 (23.5–25.6)
UPDRS part III scores in anti-PD medication OFF stateb
DBS OFF
 Item 20 and 21 (tremor) 2.3 (0–8.1)
 Total score 41.0 (35.0–83.5)
DBS ON
 Item 20 and 21 (tremor) 0 (0–0)
 Total score 21.5 (11.0–30.5)
Berg balance scale in anti-PD medication OFF stateb
DBS OFF 42 (27–50)
DBS ON 50 (41–52)
A history of falls during the past 6 months, n (%) 7 (70%)

aCalculated equivalent doses of Levodopa according to the method presented by Østergaard et al.49, and Calne50. All participants received L-dopa in their daily life, and 7/10 subjects received also dopamine agonists.

bUPDRS part III: Unified Parkinson’s disease Rating Scale, motor examination. The maximum total score is 108 points (higher scores = more severe motor symptoms). The Berg Balance scale has a scoring range from 0–56 points (higher scores = better). The evaluations were performed in anti-PD medication OFF state. All anti-Parkinsonian medications were withdrawn overnight for 10–12 h. The UPDRS assessments and balance assessments were done at the same occasion as the assessments of posture.