Table 1.
Clinical characteristics at primary breast cancer of the 41 patients with available primary tumor material.
| All (n = 46) | Luminal A-like (n = 6) | Luminal B-like (n = 6) | TNBC (n = 23) | HER2 + (n = 11) | |
|---|---|---|---|---|---|
| Age at diagnosis of BC (years) | |||||
| Mean (standard deviation) (SD) | 49 (9.9) | 54 (10.1) | 50 (8.2) | 46 (9.5) | 46 (9.3) |
| Median (min; max) | 51 (32;72) | 58 (40; 64) | 51 (41; 60) | 54 (32; 67) | 45 (33; 55) |
| Stage at diagnosis of BC | |||||
| I | 7 (15%) | 0 (0%) | 2 (33%) | 2 (9%) | 3 (27%) |
| II | 13 (28%) | 2 (33%) | 2 (33%) | 6 (26%) | 3 (27%) |
| III | 20 (44%) | 3 (50%) | 2 (33%) | 11 (48%) | 4 (36%) |
| IV | 6 (13%) | 1 (17%) | 0 | 4 (17%) | 1 (9%) |
| Histological subtype | |||||
| Ductal invasive | 42 (91%) | 6 (100%) | 5 (83%) | 22 (96%) | 9 (82%) |
| Lobular invasive | 3 (7%) | 0 (0%) | 0 (0%) | 1 (4%) | 2 (18%) |
| Other | 1 (2%) | 0 (0%) | 1 (17%) | 0 (0%) | 0 |
| BRE grade | |||||
| II | 12 (26%) | 2 (33%) | 1 (20% | 6 (26%) | 3 (27%) |
| III | 34 (74%) | 4 (67%) | 5 (80%) | 17 (24%) | 8 (73%) |
| Brain metastasis free interval (months) (n = 46) | |||||
| Mean (SD) | 48 (52.26) | 58 (45) | 74 (21) | 39 (38) | 63 (34) |
| Median (min; max) | 51 (11; 288) | 49 (0; 113) | 73 (48; 97) | 33 (0; 196) | 51 (34; 113) |
BRE (Bloom–Richardson–Elston system, with 1–3 being grade I, BRE 4–7 grade II, and BRE 8–9 grade III.