Table 2.
Clinical data of the 52 patients with available brain metastasis.
| All (n = 57) | Luminal B-like (n = 14) | TNBC (n = 26) | HER2+ (n = 17) | |
|---|---|---|---|---|
| Age at diagnosis of BM (years) | ||||
| Mean (SD) | 53 (10.9) | 55 (10) | 54 (10.7) | 49 (11) |
| Median (min; max) | 53 (29; 75) | 55 (40; 70) | 56 (29; 72) | 44 (36; 75) |
| Brain metastasis prior to other metastases | ||||
| BM only | 19 (33%) | 5 (36%) | 5 (19%) | 9 (53%) |
| BM after extra cranial mets | 22 (39%) | 4 (28%) | 13 (50%) | 5 (29%) |
| BM before extra cranial mets | 16 (28%) | 5 (36%) | 8 (31%) | 3 (18%) |
| Location of BM | ||||
| Cerebrum only | 33 (58%) | 8 (57%) | 16 (62%) | 10 (59%) |
| Cerebellum only | 15 (26%) | 5 (36%) | 8 (31%) | 2 (12%) |
| Multiple locations | 9 (16%) | 1 (7%) | 2 (7%) | 5 (29%) |
| Meningeal carcinosis | 5 (9%) | 1 (4%) | 4 (24%) | |
| Treatment for local control | ||||
| None (material from autopsy) | 2 (4%) | 1 (4%) | 1 (6%) | |
| Surgical resection | 16 (28%) | 2 (14%) | 10 (38%) | 4 (24%) |
| Surgical resection followed | 39 (68%) | 12 (86% | 15 (58%) | 12 (70%) |
| By radiotherapy | ||||
| Number of BM | ||||
| 1 | 48 (84%) | 13 (93%) | 23 (88%) | 13 (76%) |
| 2 or more | 9 (16%) | 1 (7%) | 3 (12%) | 4 (24%) |