Table 3.
Factors of depression stratified by oral cancer subgroup by using Cox regression.
| Subgroup | Oral cancer | Depression | Oral cancer vs. non-oral cancer | Oral cancer vs. non-cancer | ||||
|---|---|---|---|---|---|---|---|---|
| n | n | Adjusted HR | 95% CI | p | Adjusted HR | 95% CI | p | |
| Total | 3031 | 69 | 1.112 | 0.834–1.482 | 0.424 | 2.224 | 1.641–3.013 | < 0.001 |
| Lip | 231 | 8 | 1.276 | 0.617–2.638 | 0.486 | 2.379 | 1.148–4.930 | 0.001 |
| Tongue | 1031 | 26 | 1.368 | 0.900–2.080 | 0.127 | 2.539 | 1.645–3.920 | < 0.001 |
| Major salivary glands | 35 | 0 | 0.000 | – | 0.944 | 0.000 | – | 0.942 |
| Gum | 194 | 5 | 1.086 | 0.443–2.662 | 0.842 | 2.163 | 1.083–5.339 | 0.020 |
| Floor of mouth | 118 | 3 | 1.328 | 0.420–4.205 | 0.599 | 2.791 | 1.010–8.949 | 0.031 |
| Cheek mucosa | 686 | 13 | 1.291 | 0.722–2.312 | 0.380 | 1.872 | 1.036–3.380 | 0.029 |
| Others | 736 | 14 | 0.819 | 0.471–1.423 | 0.462 | 2.326 | 1.323–4.091 | < 0.001 |
HR hazard ratio, CI confidence interval, Adjusted HR adjusted variables listed in Table 2.