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. 2021 Dec 7;11:23524. doi: 10.1038/s41598-021-02996-4

Table 3.

Factors of depression stratified by oral cancer subgroup by using Cox regression.

Subgroup Oral cancer Depression Oral cancer vs. non-oral cancer Oral cancer vs. non-cancer
n n Adjusted HR 95% CI p Adjusted HR 95% CI p
Total 3031 69 1.112 0.834–1.482 0.424 2.224 1.641–3.013  < 0.001
Lip 231 8 1.276 0.617–2.638 0.486 2.379 1.148–4.930 0.001
Tongue 1031 26 1.368 0.900–2.080 0.127 2.539 1.645–3.920  < 0.001
Major salivary glands 35 0 0.000 0.944 0.000 0.942
Gum 194 5 1.086 0.443–2.662 0.842 2.163 1.083–5.339 0.020
Floor of mouth 118 3 1.328 0.420–4.205 0.599 2.791 1.010–8.949 0.031
Cheek mucosa 686 13 1.291 0.722–2.312 0.380 1.872 1.036–3.380 0.029
Others 736 14 0.819 0.471–1.423 0.462 2.326 1.323–4.091  < 0.001

HR hazard ratio, CI confidence interval, Adjusted HR adjusted variables listed in Table 2.